{"id":256300,"date":"2023-10-10T12:59:30","date_gmt":"2023-10-10T10:59:30","guid":{"rendered":"https:\/\/www.fqeuskadi.org\/?p=256300"},"modified":"2023-10-10T12:59:35","modified_gmt":"2023-10-10T10:59:35","slug":"cftr-modulatzaileek-funtzio-pankreatikoa-hobetzen-dute","status":"publish","type":"post","link":"https:\/\/www.fqeuskadi.org\/eu\/cftr-modulatzaileek-funtzio-pankreatikoa-hobetzen-dute\/","title":{"rendered":"CFTR modulatzaileek funtzio pankreatikoa hobetzen dute, ikerketa baten arabera"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;section&#8221; _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_row admin_label=&#8221;row&#8221; _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.20.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3 class=\"p1\">Pankrea-gutxiegitasuna fibrosi kistikoaren sintoma arrunta da<\/h3>\n<p class=\"p3\">Duela gutxi egindako ikerketa batean, <b>CFTR modulatzailearekin egindako terapia<\/b> elastasa-1 <b>entzima pankreatikoaren<\/b> (FE-1) maila fekalen igoerekin lotu zen, eta horrek funtzio pankreatiko hobea erakusten du, <b>Fibrosi Kistikoa<\/b> (FK) duten paziente gazteen artean.<\/p>\n<blockquote>\n<p class=\"p3\">Pazienteen azpimultzo txiki batek FE-1 <b>maila aski altuak<\/b> lortu zituen, pankrea-gutxiegitasuna (PI) ez zutela aintzat hartu arte; FKaren sintoma arrunta da, pankreak digestiorako behar adina entzima askatzen ez dituena.<b> Adin goiztiarragoan<\/b> CFTR moduladoreak erabiltzen hasi ziren pazienteek funtzio <b>pankreatikoan onura handienak lortzeko joera<\/b> izan zuten.<\/p>\n<p class=\"p3\">&#8220;Ikerlan honek FE-1 probak babesten ditu CFTRren edozein terapia modulatzaile jasotzen duten haurren artean&#8221;, idatzi zuten ikertzaileek. &#8220;Hala ere, datu prospektibo gehigarriak behar dira hobeto identifikatzeko nor izan behar den ebaluatua eta terapia hasi ondorengo zein denbora-tartetan&#8221;.<\/p>\n<\/blockquote>\n<h3 class=\"p6\">FE-1era konektatutako CFTR moduladoreak handitu egiten dira<\/h3>\n<p class=\"p3\">CFTR modulatzaileen bidezko terapia erabiltzeak, oro har CFTR proteinaren funtzioa handitzera jotzen dutenak, saiakuntza klinikoetan FE-1en izandako handitzearekin lotu da, eta horrek adierazten du <b>terapia horiek ere lagun dezaketela funtzio pankreatikoa hobetzen<\/b>.<\/p>\n<p class=\"p3\">CFTR moduladoreek pankrea-funtzioan mundu errealean dituzten ondorioei buruzko informazio gehiago lortzeko, zientzialariek FE-1 mailak ebaluatu zituzten FK duten <b>paziente gazteetan<\/b>, CFTR eta PERT moduladoreekin terapia jaso baitzuten AEBetako FK-ko hiru arreta-zentrotan.<\/p>\n<p><a href=\"https:\/\/www.fqeuskadi.org\/eu\/aebetan-fibrosi-kistikoa-duten-pazienteak-gehiago-bizi-dira\/\">Beste albisteak: AEBetan fibrosi kistikoa duten pazienteak gehiago bizi dira orain, 20 urteko joeren datuek erakusten dutenez.<\/a><\/p>\n<p><a href=\"https:\/\/cysticfibrosisnewstoday.com\/news\/cftr-modulators-improved-pancreatic-function-cf-study\/\">Jatorrizko albistea<\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Pankrea-gutxiegitasuna fibrosi kistikoaren sintoma arrunta da Duela gutxi egindako ikerketa batean, CFTR modulatzailearekin egindako terapia elastasa-1 entzima pankreatikoaren (FE-1) maila fekalen igoerekin lotu zen, eta horrek funtzio pankreatiko hobea erakusten du, Fibrosi Kistikoa (FK) duten paziente gazteen artean. Pazienteen azpimultzo txiki batek FE-1 maila aski altuak lortu zituen, pankrea-gutxiegitasuna (PI) ez zutela aintzat hartu arte; [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":256298,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[47],"tags":[],"class_list":["post-256300","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-fq-berriak"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>CFTR modulatzaileek funtzio pankreatikoa hobetzen dute<\/title>\n<meta name=\"description\" content=\"Ikerketa batean, CFTR modulatzailearekin egindako terapia elastasa-1 entzima pankreatikoaren maila fekalen igoerekin lotu zen.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, 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